Publications

2020

Fujita, R., Jamet, S., Lean, G., Cheng, H.C.M., Hebert, S., Kleinman, C.K., Crist C. Satellite cell expansion is mediated by P-eIF2α dependent Tacc3 translation.  Development (2020).

2019

Lean G, Halloran MW, Marescal O, Jamet S, Lumb JP, Crist C.  Ex Vivo Expansion of Skeletal Muscle Stem Cells with a Novel Small Compound Inhibitor of eIF2α Dephosphorylation. Regenerative Medicine Frontiers (2019).

Scaramozza A, Park D, Swapna K, Beerman I, Sun X, Rossi Rossi DJ, Lin CP, Scadden DT, Crist C, Brack S.  Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress. Cell Stem Cell (2019).

2018

Fujita R, Crist C. Translational Control of the Myogenic Program in Developing, Regenerating and Diseased Skeletal Muscle.  Curr Top Dev Biol (2018).

2017

Fujita R., Zismanov V., Jacob JM., Jamet S., Asiev, K. and Crist. C. Fragile X Mental Retardation Protein Regulates Skeletal Muscle Stem Cell Activity by Regulating the Stability of Myf5 mRNA. Skeletal Muscle 7, 1-10 (2017).

Crist C.  Emerging new tools to study and treat muscle pathologies: genetics and molecular mechanisms underlying skeletal muscle development, regeneration, and disease. J. Pathol. 241, 264-272.

2016

Blanc, R. Vogel, G., Chen T., Crist, C. and Richard, S. Prmt7 Preserves Satellite Cell Regenerative Capacity.  Cell Reports 14, 1528-1539 (2016).

Zismanov, V. et al. Phosphorylation of eIF2a Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal. Cell Stem Cell 18, 79–90 (2016).

2012

Crist, C. G., Montarras, D. & Buckingham, M. Muscle Satellite Cells Are Primed for Myogenesis but Maintain Quiescence with Sequestration of Myf5 mRNA Targeted by microRNA-31 in mRNP Granules. Cell Stem Cell 11, 118–126 (2012).

2009

Crist, C. G. & Buckingham, M. microRNAs gain magnitude in muscle. Cell Cycle 8, 3627–3628 (2009).

Crist, C. G. et al. Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression. Proc. Natl. Acad. Sci. U.S.A. 106, 13383–13387 (2009).

Daubas, P. et al. The regulatory mechanisms that underlie inappropriate transcription of the myogenic determination gene Myf5 in the central nervous system. Dev. Biol. 327, 71–82 (2009).